KeepKey hardware wallet and USB

On Linux Mint the hardware wallet KeepKey works fine when it’s connected into an USB 2.0 connector. A webapp at ‘https://beta.shapeshift.com’ pairs to the KeepKey. My goal is to use qubes-os together with the KeepKey. In qubes-os I created a standalone VM based on Debian. In the KeepKey guide it’s mentioned that you have to use Google Chorme or Brave web browser. So Google Chrome is now installed in my standalone VM. And it works fine. I have attached KeepKey to the stand alone VM. But the hardware wallet KeepKey is not detected by the webapp. Then I found a suggestion to open the file /opt/google/chrome/google-chrome and edit the last line:
exec -a “$0” “$HERE/chrome” “$@”

and add:
–no-sandbox --user-data-dir

so the result will be:
exec -a “$0” “$HERE/chrome” “$@” --no-sandbox --user-data-dir

but … it did not solve my problem.

Do you have any ideas what to test?